Ultimate List of Medications for Type 1 and Type 2 Diabetes | Diabetes Health Page

Ultimate List of Medications for Type 1 and Type 2 Diabetes

By NaDica | Articles

Oct 24

Diabetes is a condition which happens when the blood sugar also is known as blood glucose is too high. As a matter of fact, your blood sugar is your principal source of energy which comes from the food you consume.

Furthermore, the pancreas makes this hormone by the name insulin. Moreover, the insulin helps sugar from the food to get into the cells and helps to use it for energy.

There are cases when your body does not produce any, or enough insulin or in some cases it does not use insulin as it should. What happens then is that the sugar remains in the blood and does not reach the cells.

In fact, there are 2 kinds of diabetes, the most common diabetes type 2 and also diabetes type 1. People who have diabetes need drugs in order to keep the blood glucose levels normal.

The kinds of drugs which might treat you, in fact, depend on your kind of diabetes.

Drugs for Type 1 Diabetes

In case you have diabetes type 1 that means that your body is not able to produce insulin on its own. So, the goal of the treatment is to replace the insulin which your body is not able to produce.


As a matter of fact, the most common type of drug used in the treatment of type 1 diabetes is the insulin. Also, insulin is also used in the treatment of type 2 diabetes. Usually, it is given by injections, and it found in different kinds.

So, the kind of insulin you need depends on your severity of insulin depletion. Here are the following options:

Short-acting Insulin

  • Regular insulin (Novolin and Humulin)

Rapid-acting Insulin

  • Insulin lispro (Humalog)
  • Insulin aspart (FlexPen and NovoLog)
  • (Apidra) Insulin glulisine

Intermediate-acting Insulin

  • Insulin isophane (Novolin N and Humulin N)

Long-acting Insulins

  • Insulin glargine (Toujeo)
  • (Tresiba) Insulin degludec
  • (Lantus) Insulin glargine
  • Insulin determir (Levemir)

Combination Insulins

  • Ryzodeg (insulin degludec-insulin aspart)
  • NovoLog Mix 70/30 (insulin aspart protamine-insulin aspart)
  • Novolin 70/30 (human insulin NPH-human insulin regular)
  • Humalog Mix 75/25 (insulin lispro protamine-insulin lispro)
  • Humulin 70/30 (human insulin NPH-human insulin regular)
  • Humalog Mix 50/50 (insulin lispro protamine-insulin lispro)

 Amylinomimetic Medication

Pramlintide (SumlinPen 60, SymlinPen 120) is actually an amylinomimetic medication. As a matter of fact, this is an injectable medication usually used before meals.

It delays the time which your stomach needs to empty itself,  also it lowers glucagon secretion after meals and that reduces your blood glucose. Furthermore, it lowers your appetite through the central mechanism.

Drugs for Type 2 Diabetes

In case you have diabetes type 2, your body produces insulin, but it does not use it well. Therefore, this means that your body is not capable of making enough insulin to keep your blood glucose levels normal.

So, the goal of the treatment for type 2 diabetes is to aid the body to use insulin better or to remove the extra sugar in the blood.

Furthermore, you should know that most drugs for diabetes type 2 are actually oral drugs. However, there are some which are injections. Also, some people have diabetes type 2 who also need to take insulin.


These drugs lower the glucose in the liver, and they aid the fat cells to use insulin better.

However, these medications increase the chance of heart disease. In case you take one of the following drugs, your doctors will monitor the function of your heart during the treatment. So, these drugs are:

  • Pioflirazone-metformin (Actoplus Met XR, Actoplus Met)
  • Rosiglitazone (Avandia)
  • Rosiglitazone-glimepiride (Avandaryl)
  • Pioglirazone-glimepiride (Duetact)
  • Rosiglitizone-metformin (Amaryl M)
  • Pioglitazone-alogliptin (Oseni)


The biguanides lowers how much glucose your liver produces. Also, they lower how much glucose the intestines absorb, aid the muscles to absorb sugar and make the body to be more sensitive when it comes to insulin.

In fact, most common biguanide is actually metformin (Fortamet, Glucophage, Riomet, Metformin Hydrochloride ER and Glumetza).

So, metformin is found in the following drugs:

  • Metformin- sitagliptin (Janumet)
  • (Invokamet) metformin-alogliptin
  • Metformin-alogliptin(Kazano)
  • (Kombiglyze XR) metformin-saxagliptin
  • Metformin-dapaglidlozin (Xigduo XR)
  • (Avandamet) metformin-rosiglitazone
  • Metformin-empagliflozin (Synjardy)
  • (PrandiMet) metformin-repaglinide
  • Metformin-glipizide
  • (Actoplus) metformin-pioglitazone
  • (Glucovance) metformin-glyburide
  • Metformin-linafliptin (Jentadueto)

Alpha-glucosidase Inhibitors

These drugs aid the body to break down table sugar and starchy foods, and that lowers the blood glucose levels.

So, these medications are:

  • Miglitol (Glyset)
  • Acarbose (Precose)

DPP-4 Inhibitors

They help the body to produce insulin. Also,they lower blood glucose without leading to low blood glucose. These medications might also aid the pancreas to produce more insulin. So, these medications are:

  • alogliptin-metformin (Kazano)
  • sitagliptin and simvastatin (Juvisync)
  • alogliptin-pioglitazone (Oseni)
  • alogliptin (Nesina)
  • sitagliptin and simvastatin (Juvisync)
  • sitagliptin (Januvia)
  • linagliptin (Tradjenta)
  • sitagliptin-metformin (Janumet and Janumet XR)
  • linagliptin-empagliflozin (Glyxambi)
  •  saxagliptin-metformin (Kombiglyze XR)
  • linagliptin-metformin (Jentadueto)
  •  saxagliptin (Onglyza)


These drugs help the body to release insulin. In addition, in some cases, they might reduce the blood glucose too much. So, these drugs are:

  • (Prandimet) repaglinide-metformin
  • (Starlix) nateglinide
  • (Prandin) repaglinide

Glucagon-like Peptides (Incretin Mimetics)

These medications are similar to incretin which is a natural hormone. Furthermore, they increase the growth of b-cells and the amount of insulin which the body uses.

Also, they lower the appetite and the amount of glucagon which the body uses and they slow the stomach emptying. So, these drugs are:

  • dulaglutide (Trulicity)
  • albiglutide (Tanzeum)
  • liraglutide (Victoza)
  • exenatide extended-release (Bydureon)
  • exenatide (Byetta)


Although these drugs are among the oldest diabetes medications, they are still used till today. Moreover, these drugs with the help of the beta cells stimulate the pancreas, and in that way, the body produces more insulin. These drugs are:

  • tolbutamide (Orinase, Tol-Tab)
  • glimepiride (Amaryl)
  • tolazamide (Tolinase)
  • glimepiride (Amaryl)
  • chlorpropamide (Diabinese)
  • glimepiride-pioglitazone (Duetact)
  • glyburide-metformin (Glucovance)
  • glyburide (DiaBeta, Glynase, Micronase)
  • glimeperide-rosiglitazone (Avandaryl)
  • gliclazide glipizide (Glucotrol)
  • glipizide-metformin (Metaglip)

Sodium Sugar Transporter (SGLT) 2 Inhibitors

These medications prevent the kidneys from holding onto sugar. And instead of that, the body removes sugar through the urine. These drugs are:

  • dapagliflozin (Farxiga)
  • dapagliflozin-metformin (Xigduo XR)
  • canagliflozin (Invokana)
  • canagliflozin-metformin (Invokamet)
  • empagliflozin (Jardiance)
  • empagliflozin-linagliptin (Glyxambi)
  • empagliflozin-metformin (Synjardy)

Other Medications

People that have type 2 and type 2 diabetes need to take other drugs to treat conditions which are common with diabetes. Therefore, these drugs are:

  • High blood pressure drugs
  • Aspirin for the health of the heart
  • Medications for high cholesterol

Word of Caution

To sum up, now you know that there are many drugs available to treat diabetes type 1 and type 2. And all these drugs work differently when it comes to helping with the control of the blood glucose.

Also, remember it is crucial to consult your doctor about which diabetes medication is the most suitable for you. Your doctor will decide that based on many factors, such as your health, your type of diabetes and much more.

However, no matter what you take never forget, you are stronger than diabetes.